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The FDA also said
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it was concerned about similar non-prescription treatments, such as Fleet Phospho-soda, made by C.B. And the agency urged the following high-risk groups to use the products with caution. "Of the reported
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lexapro side effects sweating cases, three were biopsy-proven cases of acute phosphate
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nephropathy. "The FDA has received reports of 20 unique cases of kidney injury associated with the use of OsmoPrep," Dr. She added that there are alternatives to these preparations that
prescription generic equivalents prescription drugs both men and women. These treatments also shouldn't be used
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for bowel cleansing,
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and will get new warnings. The organization estimates that about 150,000 people will develop the disease this year alone. The onset of kidney injury in these cases varied, occurring in some within several hours of use of these products and in other cases
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up to 21 days after use." The agency said it has told the products' manufacturer, Salix Pharmaceuticals of Morrisville, N.C., to develop what's called a risk evaluation and mitigation
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strategy, to distribute a medication guide
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for patients so they're aware of the risk of kidney injury, and to conduct a post-marketing clinical trial to gauge the risk of injury. Joyce Korvick, deputy director of FDA's
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Division
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of Gastroenterology Products at the Center for Drug Evaluation and Research, said during an afternoon teleconference. FDA Puts Black-Box Warning on Bowel-Cleansing Drugs -- Two prescription drugs used to cleanse the bowel before a colonoscopy may cause kidney
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damage, the U.S. "Colonoscopies save lives," he said.
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Patients routinely take oral sodium phosphate products -- either prescription or over the counter -- to clean the intestines before a colonoscopy and other medical procedures. I think we just need to
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be cautious about the type of preparation we use and who we give it to, so that an extraordinarily rare complication is avoided. Roy, an associate professor in the department of medicine at Evanston-Northwestern Healthcare in
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Illinois, writing in an accompanying editorial in the journal, described the findings as "quite alarming." However, he stressed that warranted concerns about phosphate solutions shouldn't keep patients from undergoing colon cancer screening. "The FDA is recommending that consumers not use the over-the-counter preparations for bowel cleansing, but that these products be used under the direction of a physician," Korvick said. Earlier
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this year, researchers reporting in the Archives of Internal Medicine said the risks of oral sodium phosphate solutions and some oral sodium phosphate tablets were rare but real, particularly for elderly patients. At lower doses, however, they are safe for use as laxatives, the FDA said. So this should not dissuade people from doing one. Food and Drug Administration
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said Thursday. The FDA said that oral sodium phosphate products shouldn't be used by children under 18 years of age, or in combination with other laxatives containing sodium phosphate.

Food and Drug Administration put out an alert on oral sodium phosphate products, excluding OsmoPrep, recommending that they be "used with caution" among patients with impaired kidney function due to their high phosphate content. The FDA said it would now require a black-box warning on the oral sodium phosphate products Visicol and OsmoPrep, alerting consumers about the risk of acute phosphate nephropathy -- a type of severe kidney injury.


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